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Role of VMH ketone bodies in adjusting caloric intake to increased dietary fat content in
25 26 The objective of this study was to determine the potential role of astrocyte-derived ketone bodies 27 in regulating the early changes in caloric intake of diet induced-obese (DIO) vs. diet resistant 28 (DR) rats fed a 31.5% fat high-energy (HE) diet. After 3 d on chow or HE diet, DR and DIO rats, 29 were assessed for their ventromedial hypothalamic (VMH) ketone bodies levels and neuronal ...
متن کاملRole of VMH ketone bodies in adjusting caloric intake to increased dietary fat content in DIO and DR rats.
The objective of this study was to determine the potential role of astrocyte-derived ketone bodies in regulating the early changes in caloric intake of diet induced-obese (DIO) versus diet-resistant (DR) rats fed a 31.5% fat high-energy (HE) diet. After 3 days on chow or HE diet, DR and DIO rats were assessed for their ventromedial hypothalamic (VMH) ketone bodies levels and neuronal ventromedi...
متن کاملPublic-Coin Differing-Inputs Obfuscation and Its Applications
Differing inputs obfuscation (diO) is a strengthening of indistinguishability obfuscation (iO) that has recently found applications to improving the efficiency and generality of obfuscation, functional encryption, and related primitives. Roughly speaking, a diO scheme ensures that the obfuscations of two efficiently generated programs are indistinguishable not only if the two programs are equiv...
متن کاملThe roles of deiodinases in thyronamine biology
3-iodothyronamine (3-T1AM) and thyronamine (T0AM) are novel endogenous signaling molecules that exhibit great structural similarity to thyroid hormones but apparently antagonize classical thyroid hormone (T3) actions. The present study investigated whether thyronamines (TAMs) are substrates of the three Dio isozymes (Dio1, Dio2 and Dio3). TAMs were incubated with isozyme specific Dio preparatio...
متن کاملOntogeny of diet-induced obesity in selectively bred Sprague-Dawley rats.
Outbred Sprague-Dawley rats selectively bred for their propensity to develop diet-induced obesity (DIO) become heavier on low-fat diet than those bred to be diet resistant (DR) beginning at approximately 5 wk of age. Here we assessed the development of metabolic and neural functions for insights into the origins of their greater weight gain. From week 5 to week 10, chow-fed DIO rats gained 15% ...
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